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Nolvadex is an effective anti-estrogen that counters estrogenic related side effects of steroid therapy and is sometimes used before other anti-estrogens such as Clomid or Tamoxifen in certain circumstances. It has a greater binding affinity to the estrogen receptor than Clomid but with weaker anti-oestrogenic activity, making it more suitable when there are severe symptoms like water retention or migraine caused by the increased activity at the receptors, but less suitable when the aim is to use it in conjunction with testosterone, where Clomid is preferred because of its higher relative binding affinity to the androgen receptor and reported reduced tendency to produce associated side effects.
It is also sometimes used to treat gynecomastia, although it can cause some serious side effects as well. It is taken orally and its action will last for 12 hours maximum. The half-life of this medicine is 8 hours on average but will vary slightly depending upon the patient’s metabolism. Side effects encountered due to its usage are hot flashes, loss of libido, joint pains, headache, nausea, and vomiting.
Uses & Effects.
Nolvadex is a medication that is primarily used in the treatment of breast cancer and prostate cancer. It belongs to a group of medications known as selective estrogen receptor modulators (SERMs). It can also be used to treat osteoporosis in both men and women, only after other options have failed.
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